Title : Thymidylate synthase levels as a therapeutic and prognostic predictor in breast cancer.

Pub. Date : 1999 Nov-Dec

PMID : 10697629






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 5-FU is metabolically converted to 5-fluorouracil-2"-deoxyuridine-5"-monophosphate-(FdUMP) which is believed to inhibit DNA synthesis in neoplastic cells by forming a tightly bound ternary complex with thymidylate synthase (TS). Fluorodeoxyuridylate thymidylate synthetase Homo sapiens
2 5-FU is metabolically converted to 5-fluorouracil-2"-deoxyuridine-5"-monophosphate-(FdUMP) which is believed to inhibit DNA synthesis in neoplastic cells by forming a tightly bound ternary complex with thymidylate synthase (TS). Fluorodeoxyuridylate thymidylate synthetase Homo sapiens