Title : [Mechanisms for resistance to anticancer agents and the reversal of the resistance].

Pub. Date : 1999 Sep

PMID : 10695015






6 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Treatment of human colorectal carcinoma SW-620 cells with sodium butyrate(NaB) induced LRP in the cells and conferred resistance to Adrianycin(ADM), VCR, VP-16, gramicidin D and taxol. nab major vault protein Homo sapiens
2 Two LRP-specific ribozymes inhibited the NaB-induced expression of LRP in SW-620 cells and almost completely abolished their acquisition of the MDR phenotype. nab major vault protein Homo sapiens
3 Two LRP-specific ribozymes inhibited the NaB-induced expression of LRP in SW-620 cells and almost completely abolished their acquisition of the MDR phenotype. nab major vault protein Homo sapiens
4 Efflux of ADM from nuclei isolated from NaB-treated cells was enhanced compared with those from untreated cells and NaB-treated cells transfected with a LRP-specific ribozyme. nab major vault protein Homo sapiens
5 Efflux of ADM from nuclei isolated from NaB-treated cells was enhanced compared with those from untreated cells and NaB-treated cells transfected with a LRP-specific ribozyme. nab major vault protein Homo sapiens
6 The polyclonal antibody against LRP inhibited the enhanced efflux of ADM from nuclei isolated from NaB-treated cells. nab major vault protein Homo sapiens