Title : How self-tolerance and the immunosuppressive drug FK506 prevent B-cell mitogenesis.

Pub. Date : 2000 Feb 10

PMID : 10688206






1 Functional Relationships(s)
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Protein Name
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1 FK506 and cyclosporin are immunosuppressants which block three antigen-receptor signalling pathways (NFAT, NFkappaB and JNK), through inhibition of calcineurin, and inhibit mature lymphocyte proliferation to antigen. Tacrolimus nuclear factor kappa B subunit 1 Homo sapiens