Title : Renal responses to AT1 receptor blockade.

Pub. Date : 2000 Jan

PMID : 10678288






3 Functional Relationships(s)
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1 The kidney is an important site of action of Ang II AT1 receptor blockers because intrarenal Ang II not only vasoconstricts the renal vasculature but also reduces sodium excretion and suppresses the pressure natriuresis relationship. Sodium angiotensin II receptor, type 1a Rattus norvegicus
2 AT1 receptor blockers such as candesartan have been shown to cause significant increases in glomerular filtration rate, renal blood flow and proportionately much greater increases in sodium excretion and fractional sodium excretion. Sodium angiotensin II receptor, type 1a Rattus norvegicus
3 AT1 receptor blockers such as candesartan have been shown to cause significant increases in glomerular filtration rate, renal blood flow and proportionately much greater increases in sodium excretion and fractional sodium excretion. Sodium angiotensin II receptor, type 1a Rattus norvegicus