Title : H2O2 is required for UVB-induced EGF receptor and downstream signaling pathway activation.

Pub. Date : 1999 Dec

PMID : 10641711






2 Functional Relationships(s)
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1 We have recently shown that exposure of human keratinocytes to physiologic doses of ultraviolet B radiation (UVB) activates epidermal growth factor receptor (EGFR)/extracellular-regulated kinase 1 and 2 (ERK1/2), and p38 signaling pathways via reactive oxygen species. Reactive Oxygen Species epidermal growth factor receptor Homo sapiens
2 We have recently shown that exposure of human keratinocytes to physiologic doses of ultraviolet B radiation (UVB) activates epidermal growth factor receptor (EGFR)/extracellular-regulated kinase 1 and 2 (ERK1/2), and p38 signaling pathways via reactive oxygen species. Reactive Oxygen Species epidermal growth factor receptor Homo sapiens