Title : Binding mode of the 4-anilinoquinazoline class of protein kinase inhibitor: X-ray crystallographic studies of 4-anilinoquinazolines bound to cyclin-dependent kinase 2 and p38 kinase.

Pub. Date : 2000 Jan 13

PMID : 10633045






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The anilino group of the CDK2-bound compound was essentially coplanar with the quinazoline ring system and occupied a pocket between Lys-33 and Phe-80. Lysine cyclin dependent kinase 2 Homo sapiens