Title : The molecular basis of premature adrenarche: an hypothesis.

Pub. Date : 1999 Dec

PMID : 10626547






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 P450c17 appears to catalyze 17,20-lyase activity only if P450c17 has undergone serine phosphorylation and has access to cytochrome b5 as an allosteric cofactor. Serine cytochrome P450 family 17 subfamily A member 1 Homo sapiens
2 P450c17 appears to catalyze 17,20-lyase activity only if P450c17 has undergone serine phosphorylation and has access to cytochrome b5 as an allosteric cofactor. Serine cytochrome P450 family 17 subfamily A member 1 Homo sapiens
3 Mechanistic considerations of PCOS suggest a key role for serine phosphorylation of P450c17 in both adrenarche and some forms of heritable PCOS. Serine cytochrome P450 family 17 subfamily A member 1 Homo sapiens