Title : Zoledronate is a potent inhibitor of myeloma cell growth and secretion of IL-6 and MMP-1 by the tumoral environment.

Pub. Date : 1999 Dec

PMID : 10620064






2 Functional Relationships(s)
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1 Zoledronate is a potent inhibitor of myeloma cell growth and secretion of IL-6 and MMP-1 by the tumoral environment. Zoledronic Acid interleukin 6 Homo sapiens
2 In conclusion, the apoptosis of myeloma cells and BMSCs and the inhibition of both IL-6 and MMP-1 production induced by bisphosphonates, mainly zoledronate, could have antitumoral effects in patients with MM. Zoledronic Acid interleukin 6 Homo sapiens