Title : Identification of arfophilin, a target protein for GTP-bound class II ADP-ribosylation factors.

Pub. Date : 1999 Dec 17

PMID : 10593962






5 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Yeast two-hybrid screening of a human kidney cDNA library using the GTP-bound form of a class II ADP-ribosylation factor (ARF5) identified a novel ARF5-binding protein with a calculated molecular mass of 82.4 kDa, which was named arfophilin. Guanosine Triphosphate ADP ribosylation factor 5 Homo sapiens
2 Yeast two-hybrid screening of a human kidney cDNA library using the GTP-bound form of a class II ADP-ribosylation factor (ARF5) identified a novel ARF5-binding protein with a calculated molecular mass of 82.4 kDa, which was named arfophilin. Guanosine Triphosphate ADP ribosylation factor 5 Homo sapiens
3 Arfophilin bound only to the active, GTP-bound form of ARF5 and did not bind to GTP-ARF3, which is a class I ARF. Guanosine Triphosphate ADP ribosylation factor 5 Homo sapiens
4 The GTP-bound form of ARF5 with amino acid residues in the N terminus mutated to those in ARF4 (another class II ARF) also bound to arfophilin, suggesting it is a target protein for GTP-bound forms of class II ARFs. Guanosine Triphosphate ADP ribosylation factor 5 Homo sapiens
5 The GTP-bound form of ARF5 with amino acid residues in the N terminus mutated to those in ARF4 (another class II ARF) also bound to arfophilin, suggesting it is a target protein for GTP-bound forms of class II ARFs. Guanosine Triphosphate ADP ribosylation factor 5 Homo sapiens