Protein Name ARF GTPase 5
Organism Homo sapiens
Gene ID 381
Gene Symbol

ARF5

UniProt P84085 (ARF5_HUMAN), A4D0Z3 (A4D0Z3_HUMAN)
Relationships Total Number of functionally related compound(s) : 9
Total Number of Articles : 13
Description

ARF GTPase 5

Gene Summary

This gene is a member of the human ADP-ribosylation factor (ARF) gene family. These genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The gene products include 6 ARF proteins and 11 ARF-like proteins and constitute 1 family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2,and ARF3), class II (ARF4 and ARF5) and class III (ARF6). The members of each class share a common gene organization. [provided by RefSeq, Dec 2010]

synonyms
  • ADP-ribosylation factor 5
  • ADP ribosylation factor 5
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Properties