Title : Molecular consequences of human mast cell activation following immunoglobulin E-high-affinity immunoglobulin E receptor (IgE-FcepsilonRI) interaction.

Pub. Date : 1999 Dec 15

PMID : 10591138






1 Functional Relationships(s)
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1 The cross-linking by immunoglobulin E of its high-affinity receptor, FcepsilonRI, on mast cells initiates a complex series of biochemical events leading to degranulation and the synthesis and secretion of eicosanoids and cytokines through the action of transcription factors, such as nuclear factor-kappaB. Eicosanoids Fc epsilon receptor Ia Homo sapiens