PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10591138-1 1999 The cross-linking by immunoglobulin E of its high-affinity receptor, FcepsilonRI, on mast cells initiates a complex series of biochemical events leading to degranulation and the synthesis and secretion of eicosanoids and cytokines through the action of transcription factors, such as nuclear factor-kappaB. Eicosanoids 205-216 Fc epsilon receptor Ia Homo sapiens 69-80