Title : Negative regulation of epidermal growth factor signaling by selective proteolytic mechanisms in the endosome mediated by cathepsin B.

Pub. Date : 1999 Nov 19

PMID : 10559264






1 Functional Relationships(s)
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1 Using endosomal fractions prepared from EGF-injected rats and incubated in vitro, the EGFR was lost with a time course superimposable with the loss of phosphotyrosine content. Phosphotyrosine epidermal growth factor receptor Rattus norvegicus