Title : Carbonic anhydrase catalyzes cyanamide hydration to urea: is it mimicking the physiological reaction?

Pub. Date : 1999 Oct

PMID : 10550681






1 Functional Relationships(s)
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1 We show here that cyanamide is hydrated to urea in the presence of CAs, and that it also acts as a weak non-competitive inhibitor (K(I)=61+/-3 mM and 238+/-9 mM for hCA II and hCA I, respectively) towards the esterasic activity of these enzymes, as tested with 4-nitrophenyl acetate. 4-nitrophenyl acetate carbonic anhydrase 1 Homo sapiens