Title : Regulatory aspects of oxalate secretion in enteric oxalate elimination.

Pub. Date : 1999 Nov

PMID : 10541256






2 Functional Relationships(s)
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1 Injecting CRF rats with a specific angiotensin II (AngII) receptor (AT1) antagonist, losartan, results in a reversal of the CRF-induced net secretory flux (-13.87+/-0.08 pmol x cm(-2) x h(-1)) to an absorptive flux (+7.32+/-3.68 pmol x cm(-2) x h(-1)) by normalizing the unidirectional fluxes of oxalate. Oxalates angiotensinogen Rattus norvegicus
2 Serosal application of AngII at 10(-6), 10(-5), and 10(-4) M resulted in significant increases in the s-->m flux of oxalate (increasing deltaJsm = 4.06+/-1.2, 8.41+/-0.94, and 13.8+/-3.8 pmol x cm(-2) x h(-1), respectively). Oxalates angiotensinogen Rattus norvegicus