Title : Mitochondrial nitric-oxide synthase stimulation causes cytochrome c release from isolated mitochondria. Evidence for intramitochondrial peroxynitrite formation.

Pub. Date : 1999 Oct 29

PMID : 10531311






1 Functional Relationships(s)
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1 We show that mtNOS-induced cytochrome c release is not mediated via the mitochondrial permeability transition pore because the release was aggravated by cyclosporin A and abolished by blockade of mitochondrial calcium uptake by ruthenium red. Ruthenium Red cytochrome c, somatic Homo sapiens