Title : Cyclosporin A inhibits Ca2+-mediated upregulation of the DNA repair enzyme DNA polymerase beta in human peripheral blood mononuclear cells.

Pub. Date : 1999 Sep

PMID : 10491144






3 Functional Relationships(s)
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1 Our data show that transcription of pol beta mRNA is induced by Ca2+ and that CsA significantly inhibits PMA/ionomycin- and ionomycin-mediated upregulation of both pol beta mRNA and Pol beta protein. Tetradecanoylphorbol Acetate DNA polymerase beta Homo sapiens
2 Our data show that transcription of pol beta mRNA is induced by Ca2+ and that CsA significantly inhibits PMA/ionomycin- and ionomycin-mediated upregulation of both pol beta mRNA and Pol beta protein. Tetradecanoylphorbol Acetate DNA polymerase beta Homo sapiens
3 Our data show that transcription of pol beta mRNA is induced by Ca2+ and that CsA significantly inhibits PMA/ionomycin- and ionomycin-mediated upregulation of both pol beta mRNA and Pol beta protein. Tetradecanoylphorbol Acetate DNA polymerase beta Homo sapiens