Pub. Date : 1999
PMID : 10489165
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A253/Bax cells exhibited a significant increase in in vitro sensitivity to various anticancer drugs, including tomudex (9.5-fold), SN-38 (13.8-fold), doxorubicin (7.9-fold), taxol (3.1-fold), 5-FU (2.7-fold), and 5-FU/LV (4.5-fold). | raltitrexed | BCL2 associated X, apoptosis regulator | Homo sapiens |
| 2 | Treatment with tomudex induced the formation of Bax dimer in a drug concentration-dependent manner. | raltitrexed | BCL2 associated X, apoptosis regulator | Homo sapiens |
| 3 | Low level of Bax dimerization was also detected in parental A253 cells following tomudex exposure. | raltitrexed | BCL2 associated X, apoptosis regulator | Homo sapiens |