Title : The Glu-298-->Asp (894G-->T) mutation at exon 7 of the endothelial nitric oxide synthase gene and coronary artery disease.

Pub. Date : 1999 Jun

PMID : 10475066






3 Functional Relationships(s)
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1 The newly identified eNOS Glu-298-->Asp mutation in exon 7 is common and likely to be functional. Aspartic Acid nitric oxide synthase 3 Homo sapiens
2 We genotyped 763 white Australians undergoing coronary angiography for the eNOS Glu-298-->Asp mutation. Aspartic Acid nitric oxide synthase 3 Homo sapiens
3 In conclusion, the eNOS Glu-298-->Asp mutation is common, occurring with an allele frequency of 32.5%, but is not associated with either the occurrence or severity of CAD in the Australian population or with other established coronary risk factors assessed in our study. Aspartic Acid nitric oxide synthase 3 Homo sapiens