Title : Exacerbation of delayed cell injury after transient global ischemia in mutant mice with CuZn superoxide dismutase deficiency.

Pub. Date : 1999 Sep

PMID : 10471451






2 Functional Relationships(s)
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1 BACKGROUND AND PURPOSE: We have demonstrated that copper-zinc superoxide dismutase (CuZn-SOD), a cytosolic isoenzyme of SODs, has a protective role in the pathogenesis of superoxide radical-mediated brain injury. Superoxides superoxide dismutase 1, soluble Mus musculus
2 Using mice bearing a disruption of the CuZn-SOD gene (Sod1), the present study was designed to clarify the role of superoxide anion in the pathogenesis of selective vulnerability after transient global ischemia. Superoxides superoxide dismutase 1, soluble Mus musculus