Title : Drug-induced apoptosis and p53, BCL-2 and BAX expression in breast cancer tissues in vivo and in fibroblast cells in vitro.

Pub. Date : 1999 Jul

PMID : 10470656






2 Functional Relationships(s)
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1 However, in the p53 negative subgroup (n = 36), AI and BAX scores were higher and BCL-2 scores lower in the 5"-DFUR group than in the control group (P = 0.006, 0.008 and 0.050, respectively). 5"-dfur BCL2 apoptosis regulator Homo sapiens
2 CONCLUSIONS: Preoperative treatment with 5"-DFUR induced apoptosis and changes in BCL-2 and BAX expression in p53 negative breast cancers. 5"-dfur BCL2 apoptosis regulator Homo sapiens