Title : The procoagulant effect of thrombin on fibrin(ogen)-bound platelets.

Pub. Date : 1998 Nov-Dec

PMID : 10461011






2 Functional Relationships(s)
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1 Second, in platelet-fibrinogen microaggregates that were preformed in the presence of adrenaline, thrombin/CaCl(2) induced PS exposure and bleb formation of about 35% of the cells. Calcium Chloride coagulation factor II, thrombin Homo sapiens
2 These results indicate that, in the absence of coagulating plasma, thrombin is a moderate inducer of the procoagulant response of platelets, once integrin alpha(IIb)beta(3)-mediated interactions are stimulated (by adrenaline) and CaCl(2) is present. Calcium Chloride coagulation factor II, thrombin Homo sapiens