Title : Age-associated alterations in splenic iNOS regulation: influence of constitutively expressed IFN-gamma and correction following supplementation with PPARalpha activators or vitamin E.

Pub. Date : 1999 Aug 1

PMID : 10448012






1 Functional Relationships(s)
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1 Reestablishment of normal redox balance following dietary supplementation of aged mice with activators of the peroxisome proliferator-activated receptor alpha or the antioxidant alpha-tocopherol (vitamin E) restored appropriate regulation over both the production of IFN-gamma and the secretion of nitric oxide. Nitric Oxide peroxisome proliferator activated receptor alpha Mus musculus