Title : Potent bivalent thrombin inhibitors: replacement of the scissile peptide bond at P(1)-P(1)' with arginyl ketomethylene isosteres.

Pub. Date : 1999 Aug 12

PMID : 10447955






1 Functional Relationships(s)
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Protein Name
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1 The P(1)" residue is a natural or unnatural amino acid; specifically, the incorporation of mercaptoacetic acid exhibited superiority in synthesis and affinity for thrombin. 2-mercaptoacetate coagulation factor II, thrombin Homo sapiens