Pub. Date : 1999 Jun
PMID : 10429966
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Detoxification of ammonia by glutamine synthetase may be limited due to a shortage of glutamate when the nitrogen load is high. | Glutamic Acid | glutamate-ammonia ligase | Rattus norvegicus |
2 | On the basis of these changes in mRNA levels, we conclude that: (a) glutamate is produced pericentrally in sufficient amounts to allow ammonia detoxification by glutamine synthetase and (b) in addition to the catalytic role of ornithine in the periportally localized ornithine cycle, pericentral ornithine degradation provides glutamate for ammonia detoxification. | Glutamic Acid | glutamate-ammonia ligase | Rattus norvegicus |