Pub. Date : 1999 Sep
PMID : 10427140
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The human gene for cMOAT (<canalicular multispecific organic anion transporter>), a homologue of MRP, is thought to mediate hepatobiliary excretion of organic anions and to be associated with cisplatin resistance. | Cisplatin | ATP binding cassette subfamily C member 2 | Homo sapiens |
| 2 | Seven of the HCC and HB cell lines that had overexpression of the cMOAT gene were shown to be highly resistant to cisplatin compared to 2 HCC cell lines with low levels of cMOAT expression. | Cisplatin | ATP binding cassette subfamily C member 2 | Homo sapiens |
| 3 | These findings suggest that overexpression of cMOAT could contribute to cisplatin resistance in HCC and HB. | Cisplatin | ATP binding cassette subfamily C member 2 | Homo sapiens |