Title : Tumour necrosis factor-alpha mediates carrageenin-induced knee-joint incapacitation and also triggers overt nociception in previously inflamed rat knee-joints.

Pub. Date : 1999 Jul

PMID : 10422663






1 Functional Relationships(s)
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1 Our results support the conclusion that TNF alpha is a mediator of CG-induced inflammatory incapacitation, and is able to induce the further release of kinins and leukotrienes, which is suggested to have an important role in the maintenance of long-lasting nociceptive response. Leukotrienes tumor necrosis factor Rattus norvegicus