Title : Potent inhibition of the cytochrome P-450 3A-mediated human liver microsomal metabolism of a novel HIV protease inhibitor by ritonavir: A positive drug-drug interaction.

Pub. Date : 1999 Aug

PMID : 10421617






1 Functional Relationships(s)
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1 In the present study, the effect of ritonavir, a potent inhibitor of cytochrome P-450 (CYP) 3A, on the in vitro metabolism of ABT-378 was examined. Lopinavir cytochrome P450 family 3 subfamily A member 4 Homo sapiens