Title : Potent neuroprotective properties against the Alzheimer beta-amyloid by an endogenous melatonin-related indole structure, indole-3-propionic acid.

Pub. Date : 1999 Jul 30

PMID : 10419516






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In the process of screening indole compounds for neuroprotection against Abeta, potent neuroprotective properties were uncovered for an endogenous related species, indole-3-propionic acid (IPA). ipa amyloid beta precursor protein Homo sapiens
2 IPA completely protected primary neurons and neuroblastoma cells against oxidative damage and death caused by exposure to Abeta, by inhibition of superoxide dismutase, or by treatment with hydrogen peroxide. ipa amyloid beta precursor protein Homo sapiens