Title : Success of pyridostigmine, physostigmine, eptastigmine and phosphotriesterase treatments in acute sarin intoxication.

Pub. Date : 1999 Jun 15

PMID : 10403635






2 Functional Relationships(s)
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1 Both the phosphotriesterase and physostigmine treatments protected the brain AChE activities measured 24 h after sarin exposure. Physostigmine acetylcholinesterase Mus musculus
2 In phosphotriesterase and physostigmine-treated mice, a 4- and 2-fold higher sarin dose, respectively, was needed to cause a 50% inhibition of brain AChE activity. Physostigmine acetylcholinesterase Mus musculus