Title : Regulation of glucose transport by hypoxia.

Pub. Date : 1999 Jul

PMID : 10401038






1 Functional Relationships(s)
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1 The transcriptional effect of hypoxia is mediated by dual mechanisms operating in parallel, namely, (1) enhancement of Glut1 gene transcription in response to a reduction in oxygen concentration per se, acting through the hypoxia-signaling pathway, and (2) stimulation of Glut1 transcription secondary to the associated inhibition of oxidative phosphorylation during hypoxia. Oxygen solute carrier family 2 member 1 Homo sapiens