Title : PTEN interactions with focal adhesion kinase and suppression of the extracellular matrix-dependent phosphatidylinositol 3-kinase/Akt cell survival pathway.

Pub. Date : 1999 Jul 16

PMID : 10400703






1 Functional Relationships(s)
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1 Moreover, overexpression of FAK in PTEN-transfected cells reversed the decreased FAK phosphorylation and PI 3-K activity, and it partially rescued PIP3 levels, Akt phosphorylation, and PTEN-induced apoptosis. PIP3 protein tyrosine kinase 2 Homo sapiens