Title : Induction of apoptosis and differentiation by fludarabine in human leukemia cells (U937): interactions with the macrocyclic lactone bryostatin 1.

Pub. Date : 1999 Jul

PMID : 10400420






2 Functional Relationships(s)
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Protein Name
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1 Enforced expression of Bcl-2 partially protected cells from fludarabine-related apoptosis, an effect that was overcome, in part, by subsequent exposure of cells to bryostatin 1. fludarabine BCL2 apoptosis regulator Homo sapiens
2 Interestingly, Bcl-2-overexpressing cells were as or in some cases, more susceptible to differentiation induction by fludarabine (+/- bryostatin 1) than their empty vector-containing counterparts. fludarabine BCL2 apoptosis regulator Homo sapiens