Pub. Date : 1999 Apr-Jun
PMID : 10399623
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | c-erbB-2 in serum of patients receiving fractionated paclitaxel chemotherapy. | Paclitaxel | erb-b2 receptor tyrosine kinase 2 | Homo sapiens |
| 2 | In a therapy optimizing study with weekly dose-intensified paclitaxel monotherapy (schedule: 90 mg/m2 weekly x 6, q9w), we correlated the clinical course of stage IV breast cancer in UICC criteria with the course of the shed c-erbB-2 protein fragment and the CA 27.29 serum level. | Paclitaxel | erb-b2 receptor tyrosine kinase 2 | Homo sapiens |
| 3 | While the overall response rate in the study is 36%, the response rate among c-erbB-2-positive patients is 62%, indicating a high sensitivity of c-erbB-2 positive patients to dose-intense paclitaxel treatment. | Paclitaxel | erb-b2 receptor tyrosine kinase 2 | Homo sapiens |
| 4 | While the overall response rate in the study is 36%, the response rate among c-erbB-2-positive patients is 62%, indicating a high sensitivity of c-erbB-2 positive patients to dose-intense paclitaxel treatment. | Paclitaxel | erb-b2 receptor tyrosine kinase 2 | Homo sapiens |