Pub. Date : 1999 May
PMID : 10381197
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Salicylate promotes myeloperoxidase-initiated LDL oxidation: antagonization by its metabolite gentisic acid. | Salicylates | myeloperoxidase | Homo sapiens |
| 2 | Taking into consideration, that monophenolic compounds are able to form phenoxyl radicals in presence of peroxidases, we have tested salicylate, in its ability to act as a prooxidant in the MPO system. | Salicylates | myeloperoxidase | Homo sapiens |
| 3 | Exposure of LDL preparations to MPO in presence of salicylate revealed that the drug could act as a catalyst of lipid oxidation in LDL. | Salicylates | myeloperoxidase | Homo sapiens |
| 4 | The results suggest that salicylate could act like tyrosine via a phenoxyl radical as a catalyst of LDL oxidative modification by MPO. | Salicylates | myeloperoxidase | Homo sapiens |