Title : Induction of microalbuminuria by l-arginine infusion in healthy individuals: an insight into the mechanisms of proteinuria.

Pub. Date : 1999 Jun

PMID : 10352188






3 Functional Relationships(s)
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1 Furthermore, l-arginine markedly increased the urinary excretion of beta2-microglobulin. Arginine beta-2-microglobulin Homo sapiens
2 The intense and simultaneous increment in beta2-microglobulin excretion strongly suggests that the effect of l-arginine on UAE is, in a relevant part, mediated through a blockade in the tubular protein reabsorption pathways. Arginine beta-2-microglobulin Homo sapiens
3 However, the profound differences observed in the changes induced by l-arginine on UAE and beta2-microglobulin excretion and the differences in the correlation of UAE and beta2-microglobulin with respect to GFR suggest that substantial diversity exists in the mechanisms by which l-arginine affects the renal management of albumin and beta2-microglobulin. Arginine beta-2-microglobulin Homo sapiens