Title : Regulatory mechanisms of poly(ADP-ribose) polymerase.

Pub. Date : 1999 Mar

PMID : 10331633






1 Functional Relationships(s)
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1 A detailed kinetic analysis of the automodification reaction of PARP in the presence of nicked dsDNA indicates that protein-poly(ADP-ribosyl)ation probably occurs via a sequential mechanism since enzyme-bound ADP-ribose chains are not reaction intermediates. Ribose poly(ADP-ribose) polymerase 1 Homo sapiens