Pub. Date : 1999 May
PMID : 10329249
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ca2+ is the principal activator of endothelial nitric oxide synthase (eNOS), which stimulates cyclic GMP production. | Cyclic GMP | nitric oxide synthase 3 | Homo sapiens |
| 2 | Ca2+ is the principal activator of endothelial nitric oxide synthase (eNOS), which stimulates cyclic GMP production. | Cyclic GMP | nitric oxide synthase 3 | Homo sapiens |
| 3 | The final result that the eNOS inhibitor L-NAME enhanced the histamine (100 microM) induced [Ca2+]i plateau suggests a negative feedback loop (via cGMP) of endothelial NO on its own synthesis in the regulation of endothelial [Ca2+]i signal. | Cyclic GMP | nitric oxide synthase 3 | Homo sapiens |