Title : 11 beta-Hydroxysteroid dehydrogenase.

Pub. Date : 1999

PMID : 10232052

1 Functional Relationships(s)
Compound Name
Protein Name
1 11 beta-HSD2 is a high affinity NAD-dependent dehydrogenase that protects the mineralocorticoid receptor from glucocorticoid excess; mutations in the HSD11B2 gene explain an inherited form of hypertension, the syndrome of apparent mineralocorticoid excess in which cortisol acts as a potent mineralocorticoid. NAD hydroxysteroid 11-beta dehydrogenase 2 Homo sapiens