Title : TNF-induced enterocyte apoptosis and detachment in mice: induction of caspases and prevention by a caspase inhibitor, ZVAD-fmk.

Pub. Date : 1999 Apr

PMID : 10212002






1 Functional Relationships(s)
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1 The administration of a caspase inhibitor (ZVAD-fmk, 300 microg) decreased enterocyte detachment and apoptosis, as well as villus atrophy, whereas a caspase 3 inhibitor (Z-DEVD-cmk) had no effect. benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone caspase 1 Mus musculus