Pub. Date : 1999 Apr 1
PMID : 10209301
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A protein tyrosine kinase inhibitor, genistein, completely blocked both Ang II- and PMA-induced PAI-1 mRNA expression. | Genistein | angiotensinogen | Rattus norvegicus |
| 2 | Both bisindorylmaleimide I and genistein suppressed the Ang II plus TGF-beta1-induced PAI-1 mRNA upregulation to the basal level, while downregulation of PKC attenuated the synergistic upregulation of PAI-1 mRNA expression to the level comparable to TGF-beta1 alone. | Genistein | angiotensinogen | Rattus norvegicus |