Title : Targeted correction of an episomal gene in mammalian cells by a short DNA fragment tethered to a triplex-forming oligonucleotide.

Pub. Date : 1999 Apr 23

PMID : 10206960






2 Functional Relationships(s)
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Protein Name
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1 The boost in activity provided by the attached TFO domain was reduced in cells deficient in the nucleotide excision repair factor XPA but was restored in a subclone of these cells expressing XPA cDNA, suggesting a role for nucleotide excision repair in the pathway of triple helix-stimulated gene conversion. tfo XPA, DNA damage recognition and repair factor Homo sapiens
2 The boost in activity provided by the attached TFO domain was reduced in cells deficient in the nucleotide excision repair factor XPA but was restored in a subclone of these cells expressing XPA cDNA, suggesting a role for nucleotide excision repair in the pathway of triple helix-stimulated gene conversion. tfo XPA, DNA damage recognition and repair factor Homo sapiens