Title : Teratogen-induced cell death in postimplantation mouse embryos: differential tissue sensitivity and hallmarks of apoptosis.

Pub. Date : 1998 Jul

PMID : 10200514






2 Functional Relationships(s)
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1 We show that three teratogens, hyperthermia, cyclophosphamide and sodium arsenite induce an increase in cell death in day 9.0 mouse embryos with concurrent induction of DNA fragmentation, activation of caspase-3 and the cleavage of poly (ADP-ribose) polymerase (PARP). sodium arsenite poly (ADP-ribose) polymerase family, member 1 Mus musculus
2 We show that three teratogens, hyperthermia, cyclophosphamide and sodium arsenite induce an increase in cell death in day 9.0 mouse embryos with concurrent induction of DNA fragmentation, activation of caspase-3 and the cleavage of poly (ADP-ribose) polymerase (PARP). sodium arsenite poly (ADP-ribose) polymerase family, member 1 Mus musculus