Title : O- and N-demethylation of venlafaxine in vitro by human liver microsomes and by microsomes from cDNA-transfected cells: effect of metabolic inhibitors and SSRI antidepressants.

Pub. Date : 1999 May

PMID : 10192828






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Fluvoxamine (FX), at a concentration of 20 microM, decreased NDV production by 46% consistent with the capacity of FX to inhibit CYP3A, 2C9, and 2C19. Fluvoxamine cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 Fluvoxamine (FX), at a concentration of 20 microM, decreased NDV production by 46% consistent with the capacity of FX to inhibit CYP3A, 2C9, and 2C19. Fluvoxamine cytochrome P450 family 3 subfamily A member 4 Homo sapiens