Pub. Date : 1999 Apr 15
PMID : 10190974
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Conformational alteration in serum albumin as a carrier for pyridoxal phosphate: a distinction from pyridoxal phosphate-dependent glutamate decarboxylase. | Pyridoxal Phosphate | glutamate-ammonia ligase | Homo sapiens |
| 2 | To help in understanding BSA as a carrier for pyridoxal-P, the results were compared with those for glutamate decarboxylase (GAD), a pyridoxal-P-dependent protein, which requires pyridoxal-P as the cofactor for activity. | Pyridoxal Phosphate | glutamate-ammonia ligase | Homo sapiens |
| 3 | Although BSA and GAD exhibit comparable molecular weights (66430 versus 65300), numbers of amino acid residues (582 versus 585), and binding affinity (>10(6) M-1), distinct conformational alterations occur between the two proteins upon interacting with pyridoxal-P: a small conformational change for BSA versus a large conformational change for GAD. | Pyridoxal Phosphate | glutamate-ammonia ligase | Homo sapiens |