Pub. Date : 1999 Mar
PMID : 10103106
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Repeated cocaine administration increased levels of DeltaFosB, a Fos family transcription factor, in the striatum of wild-type mice, and this increase was abolished in DARPP-32-mutant mice. | Cocaine | protein phosphatase 1, regulatory inhibitor subunit 1B | Mus musculus |
| 2 | These data show that DARPP-32 is involved in regulating substance P expression in the striatonigral pathway, and in biochemical and behavioural plasticity with chronic administration of cocaine. | Cocaine | protein phosphatase 1, regulatory inhibitor subunit 1B | Mus musculus |