Title : Detection of poly(ADP-ribose) polymerase cleavage in response to treatment with topoisomerase I inhibitors: a potential surrogate end point to assess treatment effectiveness.

Pub. Date : 1999 Mar

PMID : 10100720






1 Functional Relationships(s)
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1 Results from experiments performed on colon cancer xenografts also show an association between PARP cleavage and response to treatment with TPT or CPT-11. Irinotecan poly(ADP-ribose) polymerase 1 Homo sapiens