Title : Modulation of halobenzene-induced hepatotoxicity by DT-diaphorase modulators, butylated hydroxyanisole and dicoumarol: evidence for possible involvement of quinone metabolites in the toxicity of halobenzenes.

Pub. Date : 1999 Mar 8

PMID : 10092053






1 Functional Relationships(s)
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1 When mice were treated with BB at different times after the end of dietary BHA exposure, the degree of the protection against the hepatotoxicity appears to correlate to the extent of the induction of DT-diaphorase activity by BHA pretreatment. Butylated Hydroxyanisole NAD(P)H dehydrogenase, quinone 1 Mus musculus