Pub. Date : 1999 Feb
PMID : 10091603
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here we describe the first direct evidence that ALDH1 plays a physiological role in retinoic acid synthesis by analysis of retinoid signaling in Xenopus embryos, which have plentiful stores of maternally derived retinal. | Retinoids | aldehyde dehydrogenase 1 family member A1 L homeolog | Xenopus laevis |
| 2 | These findings reveal an important conserved role for ALDH1 in retinoic acid synthesis in vivo, and demonstrate that conversion of retinoids from the aldehyde form to the carboxylic acid form is a crucial regulatory step in retinoid signaling. | Retinoids | aldehyde dehydrogenase 1 family member A1 L homeolog | Xenopus laevis |
| 3 | These findings reveal an important conserved role for ALDH1 in retinoic acid synthesis in vivo, and demonstrate that conversion of retinoids from the aldehyde form to the carboxylic acid form is a crucial regulatory step in retinoid signaling. | Retinoids | aldehyde dehydrogenase 1 family member A1 L homeolog | Xenopus laevis |