Title : Trp-Lys-Tyr-Met-Val-D-Met stimulates superoxide generation and killing of Staphylococcus aureus via phospholipase D activation in human monocytes.

Pub. Date : 1999 Feb

PMID : 10088607






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Trp-Lys-Tyr-Met-Val-D-Met (WKYMVm), a peptide that stimulates phosphoinositide (PI) hydrolysis in human leukocytes, including monocytes, binds to a unique cell surface receptor and stimulates superoxide generation, killing of Staphylococcus aureus, and activation of phospholipase D (PLD) in human monocytes. Superoxides glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens
2 We suggest that the peptide stimulates PLD downstream of PLC activation and PLD activation in turn is essential for the peptide-induced immunological functions such as the superoxide generation and killing of bacteria by human monocytes. Superoxides glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens
3 We suggest that the peptide stimulates PLD downstream of PLC activation and PLD activation in turn is essential for the peptide-induced immunological functions such as the superoxide generation and killing of bacteria by human monocytes. Superoxides glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens